THE ULTIMATE GUIDE TO SISUNATOVIR HYDROCHLORIDE

Investigations to the mechanisms of action have shown that TAK-242 binds selectively to Cys747 while in the TIR area of TLR4 [23] and subsequently disrupts the ability of TLR4 to associate with TIRAP [24]. To date, TAK-242 is the sole smaller-molecule compound documented to regulate protein–protein interactions among TLR4 and its adaptor molecule